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Mutations in central carbon metabolism genes suppress defects in nucleoid position and cell division of replication mutants in Escherichia coli.

Gene - 15 Jul 2012

Maciąg-Dorszyńska Monika, Ignatowska Małgorzata, Jannière Laurent, Węgrzyn Grzegorz, Szalewska-Pałasz Agnieszka

Abstract excerpt

A genetic link of the carbon metabolism and DNA replication was recently reported for the representative of Gram-negative bacteria, Escherichia coli. Our studies showed that the viability of thermosensitive replication mutants at high temperature can be improved or fully recovered by deleting certain genes of central carbon metabolism (CCM). In order to improve our understanding of this phenomenon, in this study...

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PMID: 22565187
DOI: 10.1016/j.gene.2012.04.066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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