Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A diplotype in the lymphotoxin alpha gene is associated with differential expression of LTA mRNA induced by Gram-positive and Gram-negative bacteria.

International journal of immunogenetics - 1 Jun 2007

Temple S E L, Almeida C M, Cheong K Y, Wunderink R G, Waterer G W

Abstract excerpt

We sequenced the lymphotoxin alpha (LTA) promoter and identified LTA10G>A in strong linkage with LTA252G>A and LTA723C>A. Stimulated cells from LTA723AA: LTA252GG:LTA10AA individuals had significantly higher LTA mRNA levels than LTA723CC:LTA252AA:LTA10GG and LTA723AA:LTA252AG:LTA10GA individuals, suggesting that this diplotype may contain a functional polymorphism explaining the observed disease associations with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Escherichia coli
Share to Leukocytes, Mononuclear

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipopolysaccharides

Share to Lymphotoxin-alpha

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Share to RNA, Messenger

Share to Streptococcus pneumoniae

Source

Identifiers

PMID: 17504504
DOI: 10.1111/j.1744-313X.2007.00674.x

Genes

LTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A diplotype in the lymphotoxin alpha gene is associated with differential expression of LTA mRNA induced by Gram-positive and Gram-negative bacteria.PMID 17504504Read ↗

Four genetic polymorphisms of lymphotoxin-alpha gene and cancer risk: a systematic review and meta-analysis.Semantic proximity Read ↗

Polymorphisms in lymphotoxin alpha and CD14 genes influence TNFalpha production induced by Gram-positive and Gram-negative bacteria.Semantic proximity Read ↗

Lymphotoxin signalling in immune homeostasis and the control of microorganisms.Semantic proximity Read ↗

Positive association between lymphotoxin-alpha variation rs909253 and cancer risk: a meta-analysis based on 36 case-control studies.Semantic proximity Read ↗

Association between the lymphotoxin-alpha gene polymorphism and chagasic cardiopathy.Semantic proximity Read ↗

The common T60N polymorphism of the lymphotoxin-alpha gene is associated with type 2 diabetes and other phenotypes of the metabolic syndrome.Semantic proximity Read ↗

Associations of lymphotoxin-a (LTA) rs909253 A/G gene polymorphism, plasma level and risk of ankylosing spondylitis in a Chinese Han population.Semantic proximity Read ↗

A functional polymorphism of lymphotoxin-alpha (LTA) gene rs909253 is associated with gastric cancer risk in an Asian population.Semantic proximity Read ↗

Association of lymphotoxin alpha polymorphism with type 1 diabetes in a Tunisian population.Semantic proximity Read ↗

The genetic association between polymorphisms in lymphotoxin-α gene and ankylosing spondylitis susceptibility in Chinese group: A case-control study.Semantic proximity Read ↗

<i>Aggregatibacter actinomycetemcomitans</i> LeukotoxinSemantic proximity Read ↗

The +252A/G polymorphism in the Lymphotoxin-α gene and the risk of non-Hodgkin lymphoma: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.