A functional polymorphism of lymphotoxin-alpha (LTA) gene rs909253 is associated with gastric cancer risk in an Asian population.

doi:10.1016/j.canep.2012.05.014

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Article

A functional polymorphism of lymphotoxin-alpha (LTA) gene rs909253 is associated with gastric cancer risk in an Asian population.

Cancer epidemiology - 1 Dec 2012

Lu Renquan, Dou Xiaowei, Gao Xiang, Zhang Jing, Ni Jian, Guo Lin

Abstract excerpt

BACKGROUND: The potentially functional polymorphism, rs909253 (+252 G>A), in the intron region of the LT-α (TNF-β) gene has been implicated in the risk of gastric cancer (GC) in some individually published studies, but others have shown inconsistent and inconclusive results. METHODS: We conducted a meta-analysis to assess the association between the lymphotoxin-α gene (LTA)+252 (G>A) polymorphism and gastric...

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PMID: 22748850
DOI: 10.1016/j.canep.2012.05.014

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