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<i>Aggregatibacter actinomycetemcomitans</i> Leukotoxin

3 Mar 2010

Abstract excerpt

Aggregatibacter actinomycetemcomitans is a Gram-negative bacterium that colonizes the human oral cavity and is the causative agent for localized aggressive periodontitis (LAP), an aggressive form of periodontal disease that occurs in adolescents. A. actinomycetemcomitans secretes a protein toxin, leukotoxin (LtxA), which helps the bacterium evade the host immune response during infection. LtxA is a...

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PMID: 20200418
DOI: 10.1177/0022034510363682

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