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Article

Evolution of resistance mutations during low-level viral replication in HIV-1-infected patients treated with zidovudine/lamivudine/abacavir as a first-line regimen.

Antiviral therapy - 1 Jan 2007

Stürmer Martin, Dauer Brenda, Moesch Manfred, Haberl Annette, Mueller Axel, Locher Leo, Knecht Gaby, Hanke Nora, Doerr Hans W, Staszewski Schlomo

Abstract excerpt

OBJECTIVE: Long-term evaluation of viral evolution in patients who continued first-line therapy with zidovudine/lamivudine/abacavir (Trizivir [TZV]) in the presence of low-level viral replication and assessment of the impact of mutational patterns selected under TZV on viral load (VL), CD4+ T-cell count (CD4) and subsequent therapeutic options. DESIGN: Analysis of viral evolution based on genotypic resistance...

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PMID: 17503744
DOI: 10.1177/135965350701200102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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