Article
Effect of zidovudine resistance mutations on virologic response to treatment with zidovudine or stavudine, each in combination with lamivudine and indinavir.
Journal of acquired immune deficiency syndromes (1999) - 15 Dec 2002
Descamps Diane, Flandre Philippe, Joly Véronique, Meiffrédy Vincent, Peytavin Gilles, Izopet Jacques, Tamalet Catherine, Zeng Ai-Feng, Harel Marine, Lastère Stéphane, Aboulker Jean-Pierre, Yéni Patrick, Brun-Vézinet Françoise
Abstract excerpt
The authors studied the effect of zidovudine (ZDV) resistance mutation on virologic response to treatment with ZDV or stavudine (d4T) each in combination with lamivudine and indinavir. Viral genotyping was performed on plasma HIV-1 RNA at study entry and concerned 155 patients previously treated with ZDV, didanosine, or zalcitabine and enrolled in the NOVAVIR (Agence National de Recherche sur le SIDA [ANRS] 073)...
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