Article
Genetic evolution of HIV in patients remaining on a stable HAART regimen despite insufficient viral suppression.
Scandinavian journal of infectious diseases - 1 Jan 2005
Kristiansen Thomas B, Pedersen Anders G, Eugen-Olsen Jesper, Katzenstein Terese L, Lundgren Jens D
Abstract excerpt
Our objective was to investigate whether steadily increasing resistance levels are inevitable in the course of a failing but unchanged Highly Active Antiretroviral Therapy (HAART) regimen. Patients having an unchanged HAART regimen and a good CD4 response (100 cells/microl above nadir) despite consistent HIV-RNA levels above 200 copies/ml were included in the study. The study period spanned at least 12 months and...
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