Article
Transcriptional and physiological adaptation to defective protein-O-mannosylation in Candida albicans.
Molecular microbiology - 1 May 2007
Cantero Pilar D, Lengsfeld Christian, Prill Stephan K-H, Subanović Marina, Román Elvira, Pla Jesús, Ernst Joachim F
Abstract excerpt
Five Pmt isoforms O-mannosylate secretory proteins in Candida albicans. Comparisons of genome-wide transcript patterns of each pmt mutant revealed commonly downregulated genes involved in glycolysis and glycerol production. Increased phosphorylation of the Cek1p- but not the Mkc1p-MAP kinase, as...
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