Article
Genome-wide analysis of the response to protein glycosylation deficiency in yeast.
FEMS yeast research - 1 Dec 2006
Cullen Paul J, Xu-Friedman Rufeng, Delrow Jeffrey, Sprague George F
Abstract excerpt
Protein modification by glycosylation occurs through an essential biochemical pathway that produces mannosyl side chain substrates, which are covalently attached to proteins in the endoplasmic reticulum. We used DNA microarray analysis to characterize the cellular response to a conditional defect (pmi40-101) in the protein glycosylation pathway. Expression profiles were obtained from DNA microarrays containing...
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