Article
The -1082 interleukin-10 polymorphism is associated with acute respiratory failure after major trauma: a prospective cohort study.
Surgery - 1 Feb 2008
Schroeder Ove, Schulte Klaus-Martin, Schroeder Julia, Ekkernkamp Axel, Laun Reinhold Alexander
Abstract excerpt
BACKGROUND: Acute respiratory failure is a common, life-threatening complication after severe trauma. Polymorphisms in cytokine genes, linked to cytokine inducibility, may influence the susceptibility to acute respiratory failure and serve as risk predictors. METHODS: This PROSPECTIVE cohort study (n = 100) included Caucasian multiple trauma (Injury Severity Score [ISS] >15) patients at a level 1 trauma center in...
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