Article
The role of vicinal tyrosine residues in the function of Haemophilus influenzae ferric-binding protein A.
The Biochemical journal - 15 Nov 2010
Khambati Husain K, Moraes Trevor F, Singh Jagroop, Shouldice Stephen R, Yu Rong-hua, Schryvers Anthony B
Abstract excerpt
The periplasmic FbpA (ferric-binding protein A) from Haemophilus influenzae plays a critical role in acquiring iron from host transferrin, shuttling iron from the outer-membrane receptor complex to the inner-membrane transport complex responsible for transporting iron into the cytoplasm. In the present study, we report on the properties of a series of site-directed mutants of two adjacent tyrosine residues...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
