Article
Gene-expression analysis identifies novel RBL2/p130 target genes in endemic Burkitt lymphoma cell lines and primary tumors.
Blood - 15 Aug 2007
De Falco Giulia, Leucci Eleonora, Lenze Dido, Piccaluga Pier Paolo, Claudio Pier Paolo, Onnis Anna, Cerino Giovanna, Nyagol Joshua, Mwanda Walter, Bellan Cristiana, Hummel Michael, Pileri Stefano, Tosi Piero, Stein Harald, Giordano Antonio, Leoncini Lorenzo
Abstract excerpt
Burkitt lymphoma (BL) is a B-cell tumor whose characteristic gene aberration is the translocation t(8;14), which determines c-myc overexpression. Several genetic and epigenetic alterations other than c-myc overexpression have also been described in BL. It has been demonstrated that the RBL2/p130...
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