Article
High prevalence of genetically-determined mannose binding lectin deficiency in young children with invasive pneumococcal disease.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Oct 2014
Muñoz-Almagro C, Bautista C, Arias M T, Boixeda R, Del Amo E, Borrás C, Armiger N, Garcia L, Sauca G, Selva L, de Sevilla M F, Ciruela P, Yebenes J C, Pallares R, Lozano F
Abstract excerpt
Susceptibility to invasive pneumococcal disease (IPD) correlates with age, younger children being the group with the highest burden of disease. The relevance of the innate immune response and particularly the role of mannose-binding lectin (MBL) in combating IPD is not well known. This is a 2-year prospective study (February 2011 to March 2013) including patients with IPD who attended two hospitals from...
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