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Article

Human variants of O6-alkylguanine-DNA alkyltransferase.

DNA repair - 1 Aug 2007

Pegg Anthony E, Fang Qingming, Loktionova Natalia A

Abstract excerpt

This article summarizes the current understanding of known variant forms of the MGMT gene that encode an altered protein. Epidemiological studies have been carried out to test whether these alterations are associated with altered cancer risk. Laboratory studies using recombinant proteins and cells expressing the known variants have investigated the possible effects of these sequence alterations on the ability of...

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Source

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Identifiers

PMID: 17482892
DOI: 10.1016/j.dnarep.2007.03.012
PMCID: PMC2030992

Genes

MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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