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Article

Chemokine receptor (CCR2) genotype is associated with myocardial infarction and heart failure in patients under 65 years of age.

Journal of molecular medicine (Berlin, Germany) - 1 Jun 2003

Ortlepp Jan R, Vesper Katharina, Mevissen Vera, Schmitz Fabian, Janssens Uwe, Franke Andreas, Hanrath Peter, Weber Christian, Zerres Klaus, Hoffmann Rainer

Abstract excerpt

Inflammation is associated with atherosclerosis of coronary arteries. Chemokines have an important role in inflammation. The CCR2 chemokine receptor mediates leukocyte chemoattraction, which is involved in the pathogenesis of coronary heart disease. We prospectively studied 1960 consecutive patients aged under 65 years and referred for a first-time left ventricular catheter. Left heart catheters were analyzed by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12719858
DOI: 10.1007/s00109-003-0435-x

Genes

CCR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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