Article
Effect of interleukin-2 level and genetic variants on coronary artery disease.
Inflammation - 1 Dec 2013
Ding Ru, Gao Wenwu, Ostrodci David H, He Zhiqing, Song Yuanlin, Ma Lan, Liang Chun, Wu Zonggui
Abstract excerpt
Inflammation plays important roles in the development of atherosclerosis and coronary artery disease (CAD). Interleukin-2 (IL-2) is a proinflammatory cytokine and induces proliferation of T cells. The aim of the study was to understand the effect of IL-2 on the development of CAD from genetic polymorphism perspective and serum level perspective. IL-2 -330T/G and +114T/G polymorphisms were tested in 692 CAD cases...
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