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Article

Ena/VASP proteins have an anti-capping independent function in filopodia formation.

Molecular biology of the cell - 1 Jul 2007

Applewhite Derek A, Barzik Melanie, Kojima Shin-Ichiro, Svitkina Tatyana M, Gertler Frank B, Borisy Gary G

Abstract excerpt

Filopodia have been implicated in a number of diverse cellular processes including growth-cone path finding, wound healing, and metastasis. The Ena/VASP family of proteins has emerged as key to filopodia formation but the exact mechanism for how they function has yet to be fully elucidated. Using cell spreading as a model system in combination with small interfering RNA depletion of Capping Protein, we determined...

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Source

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Identifiers

PMID: 17475772
DOI: 10.1091/mbc.e06-11-0990
PMCID: PMC1924831

Genes

VASP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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