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Article

Promoter polymorphism G-50T of a human CYP2J2 epoxygenase gene is associated with common susceptibility to asthma.

Chest - 1 Jul 2007

Polonikov Alexey V, Ivanov Vladimir P, Solodilova Mariya A, Khoroshaya Irina V, Kozhuhov Mikhail A, Panfilov Valery I

Abstract excerpt

BACKGROUND: Cytochrome P-450 2J2 (CYP2J2) has recently been shown to be an important enzyme in the metabolism of epoxygenase-derived eicosanoids that play important functional roles in pulmonary physiology and may contribute to the pathogenesis of asthma. STUDY OBJECTIVE: The focus of our pilot study was to evaluate whether common polymorphism G-50T within the proximal promoter of human CYP2J2 gene is associated...

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Identifiers

PMID: 17475630
DOI: 10.1378/chest.07-0371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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