Article
Association of CYP2J2 polymorphism with susceptibility to psoriasis in Turkish population: a case-control study.
Anais brasileiros de dermatologia - 1 Jan 2000
Hayran Yıldız, Allı Nuran, Uysal Pınar İncel, Çandar Tuba
Abstract excerpt
BACKGROUND: Cytochrome P450 2J2 is mostly expressed in extrahepatic tissues; it metabolizes arachidonic acid to epoxyeicosatrienoic acids, with various cardio protective and anti-inflammatory effects. CYP2J2 polymorphism has been identified as a risk factor for cardiovascular diseases, but its association with psoriasis remains unknown. OBJECTIVE: To evaluate CYP2J2 polymorphism as a risk factor for psoriasis in...
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