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Expression of X‐linked genes in deceased neonates and surviving cloned female piglets

1 May 2007

Abstract excerpt

Animal cloning through somatic cell nuclear transfer (NT) is very inefficient, probably due to insufficient reprogramming of the donor nuclei, which in turn would cause the dysregulation of gene expression. X-Chromosome inactivation (XCI) is a multi-step epigenetic process utilized by mammals to achieve dosage compensation in females. Our aim was to determine if any dysregulation of X-linked genes, which would be...

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PMID: 17474099
DOI: 10.1002/mrd.20758

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