Article
Aberrant Expression and Methylation Status of Putatively Imprinted Genes in Placenta of Cloned Piglets
8 Mar 2010
Abstract excerpt
Unlike embryos derived from fertilization, most cloned embryos die during postimplantation development, and those that survive to term are frequently defective. Many of the observed defects involve placenta. Abnormal placentation has been described in several cloned species. Imprinted genes are important regulators of placenta growth, and may be subjected to faulty reprogramming during somatic cell nuclear...
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