Article
Weight gain model in prepubertal rats: prediction and phenotyping of obesity-prone animals at normal body weight.
International journal of obesity (2005) - 1 Aug 2007
Leibowitz K L, Chang G-Q, Pamy P S, Hill J O, Gayles E C, Leibowitz S F
Abstract excerpt
OBJECTIVE: Male Sprague-Dawley rats maintained from birth on a high-fat diet were examined to determine whether a specific measure before puberty can identify and allow one to characterize prepubertal rats at normal weight with high vs low risk for adult obesity. MATERIALS AND METHODS: Measures from weaning (day 21) to around puberty (day 45) were taken of weight gain, absolute body weight and daily energy intake...
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