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Article

Maternal perinatal undernutrition programs a "brown-like" phenotype of gonadal white fat in male rat at weaning.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Jul 2010

Delahaye Fabien, Lukaszewski Marie-Amélie, Wattez Jean-Sébastien, Cisse Ouma, Dutriez-Casteloot Isabelle, Fajardy Isabelle, Montel Valérie, Dickes-Coopman Anne, Laborie Christine, Lesage Jean, Breton Christophe, Vieau Didier

Abstract excerpt

Several studies indicate that maternal undernutrition sensitizes the offspring to the development of metabolic disorders, such as obesity. Using a model of perinatal maternal 50% food-restricted diet (FR50), we recently reported that rat neonates from undernourished mothers exhibit decreased leptin plasma levels associated with alterations of hypothalamic proopiomelanocortin system. The present study aimed at...

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PMID: 20463183
DOI: 10.1152/ajpregu.00604.2009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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