Article
Model for predicting and phenotyping at normal weight the long-term propensity for obesity in Sprague-Dawley rats.
Physiology & behavior - 15 Apr 2006
Dourmashkin J T, Chang G-Q, Hill J O, Gayles E C, Fried S K, Leibowitz S F
Abstract excerpt
Tests were conducted to determine whether weight gain or nutrient intake measures during the first week of exposure to a macronutrient diet can accurately predict an animal's long-term propensity towards obesity. In multiple groups of normal-weight Sprague-Dawley rats (n=35-70/group), daily weight gain during the first 5 days on a high-fat diet (45-60% fat) was found to be strongly, positively correlated (r=+0.71...
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