Article
An eight-subunit COP9 signalosome with an intact JAMM motif is required for fungal fruit body formation.
Proceedings of the National Academy of Sciences of the United States of America - 8 May 2007
Busch Silke, Schwier Elke U, Nahlik Krystyna, Bayram Ozür, Helmstaedt Kerstin, Draht Oliver W, Krappmann Sven, Valerius Oliver, Lipscomb William N, Braus Gerhard H
Abstract excerpt
Fruit body formation in filamentous fungi is a complex and yet hardly understood process. We show here that protein turnover control is crucial for Aspergillus nidulans development. Deletion of genes encoding COP9 signalosome (CSN) subunits 1, 2, 4, or 5 resulted in identical blocks in fruit body...
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