Article
The COP9 signalosome is an essential regulator of development in the filamentous fungus Aspergillus nidulans.
Molecular microbiology - 1 Aug 2003
Busch Silke, Eckert Sabine E, Krappmann Sven, Braus Gerhard H
Abstract excerpt
The COP9 signalosome (CSN) is a conserved multiprotein complex involved in regulation of eukaryotic development. The deduced amino acid sequences of two Aspergillus nidulans genes, csnD and csnE, show high identities to the fourth and fifth CSN subunits of higher eukaryotes. The csnD transcript is abundant during vegetative growth as well as development and the corresponding protein accumulates in the nucleus....
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