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Article

Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1.

Circulation - 15 May 2007

Faraday Nauder, Yanek Lisa R, Mathias Rasika, Herrera-Galeano J Enrique, Vaidya Dhananjay, Moy Taryn F, Fallin M Daniele, Wilson Alexander F, Bray Paul F, Becker Lewis C, Becker Diane M

Abstract excerpt

BACKGROUND: The inability of aspirin (acetylsalicylic acid [ASA]) to adequately suppress platelet function is associated with future risk of myocardial infarction, stroke, and cardiovascular death. Genetic variation is a proposed but unproved mechanism for insufficient ASA responsiveness. METHODS AND RESULTS: We examined platelet ASA responsiveness in 1880 asymptomatic subjects (mean age, 44+/-13 years; 58%...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17470694
DOI: 10.1161/CIRCULATIONAHA.106.667584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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