Article
Aspirin Resistance in healthy drug-naive men versus women (from the Heredity and Phenotype Intervention Heart Study).
The American journal of cardiology - 15 Aug 2009
Shen Haiqing, Herzog William, Drolet MaryAnn, Pakyz Ruth, Newcomer Sylvia, Sack Paul, Karon Heidi, Ryan Kathleen A, Zhao Yiju, Shi Xiaolian, Mitchell Braxton D, Shuldiner Alan R
Abstract excerpt
This study was designed to determine the factors that contribute to interindividual variation in the antiplatelet effects of aspirin. We measured platelet response to aspirin in 745 (400 men and 345 women) drug-naive asymptomatic subjects of the Heredity and Phenotype Intervention (HAPI) Heart Study. Whole blood platelet aggregometry was performed to assess response to arachidonic acid, adenosine diphosphate, and...
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