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Article

Modulation of chondrocyte phenotype via baculovirus-mediated growth factor expression.

Biomaterials - 1 Aug 2007

Sung Li-Yu, Lo Wen-Hsin, Chiu Hsin-Yi, Chen Huang-Chi, Chung Ching-Kuang, Lee Hsiao-Ping, Hu Yu-Chen

Abstract excerpt

Baculovirus has emerged as a new gene delivery vector thanks to a number of advantages. This study demonstrated that baculovirus conferred efficient gene delivery and mediated expression of growth factors (TGF-beta1, IGF-1 and BMP-2) to therapeutic levels in rabbit chondrocytes. Interestingly, the cellular response to growth factor stimulation was dependent on the cell passage. The highly de-differentiated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17467793
DOI: 10.1016/j.biomaterials.2007.04.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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