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Transgene expression and differentiation of baculovirus‐transduced human mesenchymal stem cells

11 Feb 2005

Abstract excerpt

BACKGROUND: Mesenchymal stem cells (MSCs) have drawn considerable attention as vehicles for cell- or gene-based therapies, yet various problems still exist for current gene delivery vectors. On the other hand, baculovirus has emerged as a novel gene therapy vector, but its transduction of stem cells has not been reported. METHODS: A recombinant baculovirus expressing the enhanced green fluorescent protein (EGFP)...

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PMID: 15712348
DOI: 10.1002/jgm.729

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