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Article

Non-viral Gene Delivery Methods for Bone and Joints

19 Nov 2020

Abstract excerpt

Viral carrier transport efficiency of gene delivery is high, depending on the type of vector. However, viral delivery poses significant safety concerns such as inefficient/unpredictable reprogramming outcomes, genomic integration, as well as unwarranted immune responses and toxicity. Thus, non-viral gene delivery methods are more feasible for translation as these allow safer delivery of genes and can modulate...

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Identifiers

PMID: 33330428
DOI: 10.3389/fbioe.2020.598466

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