Article
Human KCNQ1 S140G mutation is associated with atrioventricular blocks.
Heart rhythm - 1 May 2007
Yang Yiqing, Liu Yi, Dong Xiongjian, Kuang Ying, Lin Jie, Su Xiaoyan, Peng Luying, Jin Qingfeng, He Yusong, Liu Ban, Pan Zhiwen, Li Li, Zhu Qian, Lin Xiaoping, Zhou Qinshu, Pan Qin, Eurlings Petra M H, Fei Jian, Wang Zhugang, Chen Yi Han
Abstract excerpt
BACKGROUND: We recently reported that an S140G mutation in human KCNQ1, an alpha subunit of potassium channels, was involved in the pathogenesis of familial atrial fibrillation (AF), but it is not clear whether the mutation is associated with other cardiac arrhythmias. OBJECTIVE: The purpose of this study was to further explore the association of the KCNQ1 S140G mutation with cardiac arrhythmias. METHODS: We...
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