Article
TNFRSF13B/TACI Mutations in Patients with Chronic Rhinosinusitis with Nasal Polyps.
American journal of rhinology & allergy - 1 Jan 2023
Tsiouma Georgia K, Skoulakis Charalampos E, Lachanas Vasileios A, Sevdali Eirini G, Tsinti Gerasimina N, Florou Zoi A, Petinaki Efthymia A, Speletas Matthaios G
Abstract excerpt
BACKGROUND: The pathogenesis of Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) remains still inconclusive. Recent studies identified an increased expression of BAFF (a B cell-activating factor) and its receptor TACI (Transmembrane Activator and cAML Interactor) in nasal polyp samples, while TNFRSF13B/TACI mutations have been found in patients with benign lymphoproliferative disorders and primary antibody...
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