Article
Development of a heterologous, multigenotype vaccine against hepatitis C virus infection.
European journal of clinical investigation - 1 May 2007
Encke J, Radunz W, Eisenbach C, Geib J, Gehrke S, Pfaff E, Stremmel W
Abstract excerpt
BACKGROUND: Unquestionably viral diversity and genetic heterogeneity in hepatitis C virus (HCV) infection and other viral diseases play an essential role in viral immune escape and the development of chronicity. Despite this knowledge most vaccine approaches against HCV have excluded this importa...
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