Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune responses to hepatitis C virus structural and nonstructural proteins induced by plasmid DNA immunizations.

The Journal of infectious diseases - 1 Jan 2000

Gordon E J, Bhat R, Liu Q, Wang Y F, Tackney C, Prince A M

Abstract excerpt

DNA-based immunizations have been used to elicit cellular immunity to hepatitis C virus (HCV) proteins in mice. Mice were immunized by intramuscular or intradermal injections of plasmid DNA derived from a near-full-length HCV genotype 1b genomic clone (pRC/B2) or individual genomic clones. These immunizations induced cytotoxic T lymphocytes (CTLs), as revealed in standard chromium-release assays that used...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibody Specificity
Share to Hepatitis C Antibodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity, Cellular

Share to Vaccination

Share to Vaccines, DNA

Share to Viral Hepatitis Vaccines

Share to Viral Nonstructural Proteins

Share to Viral Structural Proteins

Source

Identifiers

PMID: 10608749
DOI: 10.1086/315162

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune responses to hepatitis C virus structural and nonstructural proteins induced by plasmid DNA immunizations.PMID 10608749Read ↗

Strong HCV NS3/4a, NS4b, NS5a, NS5b-specific cellular immune responses induced in Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine.Semantic proximity Read ↗

DNA-based immunization breaks tolerance in a hepatitis C virus transgenic mouse model.Semantic proximity Read ↗

DNA prime-canarypox boost with polycistronic hepatitis C virus (HCV) genes generates potent immune responses to HCV structural and nonstructural proteins.Semantic proximity Read ↗

Induction of Genotype Cross-Reactive, Hepatitis C Virus-Specific, Cell-Mediated Immunity in DNA-Vaccinated Mice.Semantic proximity Read ↗

DNA Immunization with Japanese Encephalitis Virus Nonstructural Protein NS1 Elicits Protective Immunity in MiceSemantic proximity Read ↗

Synthetic DNA immunogen encoding hepatitis B core antigen drives immune response in liver.Semantic proximity Read ↗

Strong HCV NS3- and NS4A-specific cellular immune responses induced in mice and Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine.Semantic proximity Read ↗

DNA vaccine cocktail expressing genotype A and C HBV surface and consensus core antigens generates robust cytotoxic and antibody responses in mice and Rhesus macaques.Semantic proximity Read ↗

Keyhole Limpet Hemocyanin-Conjugated Peptides from Hepatitis C Virus Glycoproteins Elicit Neutralizing Antibodies in BALB/c Mice.Semantic proximity Read ↗

Comparison of protective efficacies of plasmid DNAs encoding Japanese encephalitis virus proteins that induce neutralizing antibody or cytotoxic T lymphocytes in miceSemantic proximity Read ↗

Modulation of the Immune Response Induced by Gene Electrotransfer of a Hepatitis C Virus DNA Vaccine in Nonhuman PrimatesSemantic proximity Read ↗

Induction of cell-mediated immune responses in mice by DNA vaccines that express hepatitis C virus NS3 mutants lacking serine protease and NTPase/RNA helicase activities.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.