Article
Experimental vaccine activities of recombinant E1 and E2 glycoproteins and hypervariable region 1 peptides of hepatitis C virus in chimpanzees.
Archives of virology - 1 Jan 1999
Esumi M, Rikihisa T, Nishimura S, Goto J, Mizuno K, Zhou Y H, Shikata T
Abstract excerpt
A chimpanzee was immunized with two recombinant envelope glycoproteins E1 and E2 of hepatitis C virus (HCV), strain HCV-N2, and the hypervariable region 1 (HVR1) peptides of a different isolate, HCV-#6, then received an intravenous inoculation of 10 chimpanzee infectious doses of HCV-#6. With hig...
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