Article
Antiretroviral drug resistance and phylogenetic diversity of HIV-1 in Chile.
Journal of medical virology - 1 Jun 2007
Ríos Maritza, Delgado Elena, Pérez-Alvarez Lucía, Fernández Jorge, Gálvez Paula, de Parga Elena Vázquez, Yung Verónica, Thomson Michael M, Nájera Rafael
Abstract excerpt
This study reports the analysis of human immunodeficiency virus type 1 (HIV-1) protease (PR) and reverse transcriptase (RT) coding sequences from 136 HIV-1-infected subjects from Chile, 66 (49%) of them under antiretroviral (ARV) treatment. The prevalence of mutations conferring high or intermediate resistance levels to ARVs was 77% among treated patients and 2.5% among drug-naïve subjects. The distribution of...
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