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Article

Characterization of HIV-1 genetic diversity and antiretroviral resistance in the state of Maranhão, Northeast Brazil.

PloS one - 1 Jan 2020

Leal Élcio, Arrais Claudia Regina, Barreiros Marta, Farias Rodrigues Jessyca Kalynne, Silva Sousa Nilviane Pires, Duarte Costa Daniel, Rodrigo Pereira Santos Francisco Dimitre, Dantas Silva Antonio, Silva Viana Antonia Iracilda E, Barros Allan Kardec, Lima Kledoaldo

Abstract excerpt

The HIV-1 epidemic in Brazil has been growing in northeast and north regions, particularly an increase in AIDS cases among the younger male population has been observed. This study aims to characterize the HIV-1 genetic diversity and to evaluate its antiretroviral resistance profile among individuals presenting virological failure in the state of Maranhão-Brazil. HIV-1 pol gene sequences from 633 patients on...

Topics

Anti-HIV Agents
Brazil
Drug Resistance, Viral
Genetic Variation
HIV-1
Humans
pol Gene Products, Human Immunodeficiency Virus

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32218587
DOI: 10.1371/journal.pone.0230878
PMCID: PMC7100926

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