Article
HIV type 1 genetic diversity is a major obstacle for antiretroviral drug resistance hybridization-based assays.
AIDS research and human retroviruses - 10 Oct 2001
Kijak G H, Rubio A E, Quarleri J F, Salomón H
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) is characterized by high genetic diversity. Current antiretroviral (ARV) drug resistance genotyping assays have been designed on the basis of the most prevalent sequence patterns circulating in the United States and Europe, which belong to the B subtype. However, little is known about their performance on non-B subtype samples. In Argentina, circulating forms have been...
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