Article
HIV-1 subtypes and drug resistance in children during antiretroviral therapy in Brazil.
Journal of medical virology - 1 Aug 2021
de Andrade Arrais Claudia R, Lima Kledoaldo, Barreiros Marta, Rodrigues Jessyca K F, Sousa Nilviane P S, Costa Daniel D, Santos Francisco D R P, Pereira Gerson F M, E Silva Viana Antonia I, Barros Allan K, Leal Élcio
Abstract excerpt
We evaluate the genetic characterization of 132 HIV-1 pol sequences from children and adolescents undergoing antiretroviral therapy in Northeast Brazil. Phylogenetic and recombination analyses were performed using the maximum likelihood method using SeaView version 4 and SIMPLOT software. Most individuals harbored HIV-1 B (84.8%) and BF recombinants (9.8%), although other non-B subtypes were detected: HIV-1 C...
Topics
- Adolescent
- Anti-HIV Agents
- Brazil
- Child
- Child, Preschool
- Drug Resistance, Viral
- Genotype
- HIV Infections
- HIV-1
- Humans
- Mutation