Article
Detection of distinct human immunodeficiency virus type 1 circulating recombinant forms in northeast Brazil.
Journal of medical virology - 1 Dec 2011
Santos Luciane Amorim, Monteiro-Cunha Joana Paixao, Araujo Adriano Fernando, Brites Carlos, Galvao-Castro Bernardo, Alcantara Luiz Carlos Junior
Abstract excerpt
The extraordinary genetic diversity and immune evasion of human immunodeficiency virus (HIV) pose significant challenges for vaccine development and antiretroviral therapy efficacy. The objective of this study was to characterize the molecular profile of HIV-1 epidemic in Salvador, Bahia, Brazil, determining the genetic subtypes and the presence of antiretroviral resistance mutations. HIV-1 pol DNA sequences from...
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