Whole-Genome Sequencing–Based Characterization of HIV-1 in a Tertiary-Care Hospital in Mexico: Drug-Resistance Mutations and Genetic Diversity

Abstract excerpt

Human immunodeficiency virus type 1 exhibits extensive genetic diversity, which has important implications for transmission dynamics, disease progression, and the effectiveness of antiretroviral therapy. In Mexico, molecular surveillance has largely relied on partial pol gene sequencing, limiting the detection of recombination events and resistance mutations outside canonical regions. In this study, we performed n...

Topics

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• Anti-HIV Agents
• Drug Resistance, Viral
• Genome, Viral
• High-Throughput Nucleotide Sequencing
• HIV-1
• HIV Infections
• Mexico
• Tertiary Care Centers

Identifiers and source

Literature Corpus work

ed54d038-c539-5021-85f7-7dd7c7fe81d3

DOI

10.20944/preprints202605.0280.v1