Pharmacological and clinical impact of the unique molecular structure of a new plasminogen activator.

doi:10.1093/eurheartj/18.suppl_f.11

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Article

Pharmacological and clinical impact of the unique molecular structure of a new plasminogen activator.

European heart journal - 1 Dec 1997

Smalling R W

Abstract excerpt

Thrombolytic therapy has been recognized as a significant improvement in the management of acute myocardial infarction. Thrombolytic agents however have been limited by short half-lives that necessitate complex administration protocols and by the potential for bleeding complications. The native t...

Topics

Amino Acid Sequence
Animals
Fibrinolytic Agents
Humans
Molecular Sequence Data
Mutation
Plasminogen Activators
Recombinant Proteins
Tissue Plasminogen Activator

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