Article
The Hog1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in Saccharomyces cerevisiae.
Genes & development - 15 Sept 1998
O'Rourke S M, Herskowitz I
Abstract excerpt
The MAPKKK Ste11p functions in three Saccharomyces cerevisiae MAPK cascades [the high osmolarity glycerol (HOG), pheromone response, and pseudohyphal/invasive growth pathways], but its activation in response to high osmolarity stimulates only the HOG pathway. To determine what restricts cross-activation of MAPK cascades (cross talk), we have studied mutants in which the pheromone response pathway is activated by...
Topics
- Base Sequence
- Binding Sites
- Calcium-Calmodulin-Dependent Protein Kinases
- DNA Primers
- Fungal Proteins
- GTP-Binding Protein beta Subunits
- GTP-Binding Proteins
- Gene Expression
- Genes, Fungal
- Heterotrimeric GTP-Binding Proteins