Article
Genetic polymorphisms influencing arsenic metabolism: evidence from Argentina.
Environmental health perspectives - 1 Apr 2007
Schläwicke Engström Karin, Broberg Karin, Concha Gabriela, Nermell Barbro, Warholm Margareta, Vahter Marie
Abstract excerpt
The susceptibility to arsenic-induced diseases differs greatly between individuals, possibly due to interindividual variations in As metabolism that affect retention and distribution of toxic metabolites. To elucidate the role of genetic factors in As metabolism, we studied how polymorphisms in six genes affected the urinary metabolite pattern in a group of indigenous women (n = 147) in northern Argentina who...
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