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Article

Genetic polymorphisms in MTHFR 677 and 1298, GSTM1 and T1, and metabolism of arsenic.

Journal of toxicology and environmental health. Part A - 15 Jan 2007

Steinmaus Craig, Moore Lee E, Shipp Miriam, Kalman David, Rey Omar A, Biggs Mary L, Hopenhayn Claudia, Bates Michael N, Zheng Shichun, Wiencke John K, Smith Allan H

Abstract excerpt

Methylation is the primary route of metabolism of inorganic arsenic in humans, and previous studies showed that interindividual differences in arsenic methylation may have important impacts on susceptibility to arsenic-induced cancer. To date, the factors that regulate arsenic methylation in humans are mostly unknown. Urinary arsenic methylation patterns and genetic polymorphisms in methylenetetrahydrofolate...

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Source

Identifiers

PMID: 17365577
DOI: 10.1080/15287390600755240

Genes

MTHFR
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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