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Article

Arsenic metabolism is influenced by polymorphisms in genes involved in one-carbon metabolism and reduction reactions.

Mutation research - 10 Jul 2009

Schläwicke Engström Karin, Nermell Barbro, Concha Gabriela, Strömberg Ulf, Vahter Marie, Broberg Karin

Abstract excerpt

OBJECTIVES: The susceptibility to arsenic (As)-induced diseases differs greatly between individuals, probably to a large extent due to genetic differences in arsenic metabolism. The aim for this study was to identify genetic variants affecting arsenic metabolism. METHODS: We evaluated the association between urinary metabolite pattern and polymorphisms in three gene-groups related to arsenic metabolism: (1)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18682255
DOI: 10.1016/j.mrfmmm.2008.07.003

Genes

CHDH
GLRX
MTRR
PRDX2

Provenance

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