Article
The 3'UTR 1188 A/C polymorphism in the interleukin-12p40 gene (IL-12B) is associated with lepromatous leprosy in the west of Mexico.
Immunology letters - 30 Jun 2008
Alvarado-Navarro Anabell, Montoya-Buelna Margarita, Muñoz-Valle José Francisco, López-Roa Rocio Ivette, Guillén-Vargas Cecilia, Fafutis-Morris Mary
Abstract excerpt
Leprosy is a chronic infectious disease caused by Mycobacterium leprae. IL-12 participates in the immune response against M. leprae by regulating T cell differentiation into the Th1-type response. Several single nucleotide polymorphisms have been identified in the IL-12 gene such as 3'UTR 1188 A/...
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