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Article

Genetic polymorphism of catechol-O-methyltransferase and cytochrome P450c17α in preeclampsia.

Pharmacogenetics and genomics - 1 Oct 2010

Lim Ji Hyae, Kim Shin Young, Kim Do Jin, Park So Yeon, Han Ho Won, Han Jung Yeol, Lee Si Won, Yang Jae Hyug, Ryu Hyun Mee

Abstract excerpt

OBJECTIVE: Catechol-O-methyltransferase (COMT) and cytochrome P450c17α (CYP17A1) are key enzymes involved in the metabolism of steroid hormones; genetic polymorphisms in these genes affect enzyme activity. Recently, functional polymorphisms in the COMT and CYP17A1 genes have been suggested as a s...

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Source

Identifiers

PMID: 20729792
DOI: 10.1097/FPC.0b013e32833df033

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20729792-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Genetic polymorphism of catechol-O-methyltransferase and cytochrome P450c17α in preeclampsia.PMID 20729792Read ↗

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