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Article

Relationship between oxidative stress levels and activation state on a hepatic stellate cell line.

Liver international : official journal of the International Association for the Study of the Liver - 1 May 2006

Guimarães E L M, Franceschi M F S, Grivicich I, Dal-Pizzol F, Moreira J C F, Guaragna R M, Borojevic R, Margis R, Guma F C R

Abstract excerpt

BACKGROUND/AIMS: Oxidative stress plays an important role in liver fibrosis. Under pathological conditions, hepatic stellate cells (HSC) undergo an activation process, developing a myofibroblast-like phenotype from the lipocyte phenotype. In this study, we determined the levels of oxidative stress and proliferation in different activation states of an experimental model of mouse HSC, the GRX cell line. These...

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PMID: 16629652
DOI: 10.1111/j.1478-3231.2006.01245.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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